Skip to main content
. 2011 Nov 18;11(2):M111.010132. doi: 10.1074/mcp.M111.010132

Table II. PKA-mediated phosphorylation: semi-quantitative comparison of native and CuOOH-inactivated CYP3A4.

The values are the means ± S.D. of three individual determinations. Control samples had no detectable (—) phosphorylated peptides.

No. Residue Control Native 3A4 (%) CuOOH-3A4 (%)
1 Ser-116 0.20 ± 0.05 0.27 ± 0.08
2 Ser-119 0.01 ± 0.004 0.42 ± 0.06
3 Ser-134 0.04 ± 0.01 0.06 ± 0.03
4 Ser-259 0.49 ± 0.05
5 Ser-478 0.32 ± 0.07 1.29 ± 0.12