Table I. Number of putative autoantigens detected per individual in the screening of NAPPA array GST#1.
For each target protein, the mean and standard deviation of the control cohort was calculated. Z scores ((signal − mean)/(standard deviation)) were calculated for every query protein in every individual in the three groups. Proteins with Z scores greater than 3 are assigned as positive hits.
| Healthy controls |
AS patients |
RA patients |
|||
|---|---|---|---|---|---|
| Sample name | No. of putative autoantigens detected | Sample name | No. of putative autoantigens detected | Sample name | No. of putative autoantigens detected |
| HC1 | 0 | AS1 | 10 | RA1 | 1 |
| HC2 | 0 | AS2 | 3 | RA2 | 231 |
| HC3 | 0 | AS3 | 3 | RA3 | 5 |
| HC4 | 0 | AS4 | 7 | RA4 | 12 |
| HC5 | 0 | AS5 | 136 | RA5 | 120 |
| HC6 | 1 | AS6 | 0 | RA6 | 39 |
| HC7 | 1 | AS7 | 244 | RA7 | 3 |
| HC8 | 0 | AS8 | 2 | RA8 | 1 |
| HC9 | 7 | AS9 | 11 | RA9 | 0 |
| HC10 | 0 | AS10 | 219 | RA10 | 0 |
| HC11 | 0 | AS11 | 152 | RA11 | 11 |
| HC12 | 2 | AS12 | 2 | RA12 | 3 |
| HC13 | 1 | AS13 | 218 | RA13 | 3 |
| HC14 | 0 | AS14 | 7 | RA14 | 130 |
| HC15 | 0 | AS15 | 3 | RA15 | 0 |
| HC16 | 1 | AS16 | 0 | RA16 | 10 |
| HC17 | 1 | AS17 | 1 | RA17 | 2 |
| HC18 | 0 | AS18 | 158 | ||
| HC19 | 1 | AS19 | 26 | ||
| HC20 | 0 | AS20 | 2 | ||
| HC21 | 0 | AS21 | 6 | ||
| HC22 | 0 | AS22 | 94 | ||
| HC23 | 182 | AS23 | 2 | ||
| HC24 | 0 | AS24 | 0 | ||
| HC25 | 1 | AS25 | 3 | ||