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. 2010 May 8;9(9):678–684. doi: 10.4161/cbt.9.9.11436

Figure 2.

Figure 2

mRNA expression of the retinoid regulated CRABP2 gene was assessed in peripheral blood mononuclear cells (PBMC) derived cDNA using reverse transcriptase PCR. Expression of CRABP2 was not detected in four patients prior to initiation of treatment (baseline, samples 1–4). Expression of CRABP2 was detectable following four treatments courses, immediately prior to the fifth course (samples 5 and 8: N = 2) and sixth treatment courses (sample 10). Expression of CRABP2 persists following the fifth (samples 6 and 8: 2 h post infusion; sample 7 and 9: 24 h post infusion) and sixth (sample 11: 2 h post infusion) drug infusions. Expression of GAPDH was used to confirm cDNA integrity.