Table 3.

Summary of correlative studies

Patient no.	IHC				IL-6 level (pg/mL) by ELISA
(N = 7)	p27	Ki-67	RB	p-RB	Pre-treatment	Pre-second treatment	At disease progression
UCD-001	30%	30%	30%	0	1.8	–	12.5
UCD-002	0	50%	60%	0	110.5	328.7	213.2
UCD-003	90%	60%	–	–	0	0.3	10.9
UCD-004	80%	35%	0	0	6.3	7.8	16.7
UCD-005	90%	40%	–	–	–	–	–
UCD-006	100%	90%	–	–	2.6	5.0	6.0
UCD-007	0	10%	0	0	3.7	13.5	7.8

IHC immunohistochemistry stain. ELISA Enzyme-Linked Immunosorbent Assay

The reported normal value for IL-6 was 4.3 pg/mL