Table II.
Estimates of mean locus-specific heritability ± standard deviation for the family-based samples averaged over all 200 replicates for Q1 and Q2 in descending order based on ROMP result
| Causal SV | Gene | (ROMP) | |||
|---|---|---|---|---|---|
| Q1 | C4S4935 | VEGFC | 0.250 ± 0.066 | 0.182 ± 0.040 | |
| C6S2981 | VEGFA | 0.230 ± 0.057 | 0.173 ± 0.036 | ||
| C13S523 | FLT1 | 0.046 ± 0.018 | 0.042 ± 0.014 | ||
| C4S1878 | KDR | 0.044 ± 0.026 | 0.030 ± 0.014 | ||
| C4S1884 | KDR | 0.018 ± 0.016 | 0.020 ± 0.011 | ||
| C13S431 | FLT1 | 0.017 ± 0.018 | 0.019 ± 0.012 | ||
| C13S522 | FLT1 | 0.008 ± 0.008 | 0.014 ± 0.008 | ||
| C19S4831 | HIF3A | 0.001 ± 0.007 | 0.004 ± 0.004 | ||
| C13S514 | FLT1 | 0.000 ± 0.003 | 0.002 ± 0.002 | ||
| C4S1861 | KDR | 0.000 ± 0.003 | 0.002 ± 0.002 | ||
| C4S1873 | KDR | 0.000 ± 0.004 | 0.002 ± 0.002 | ||
| C1S6533 | ARNT | −0.001 ± 0.007 | 0.003 ± 0.004 | ||
| C1S6540 | ARNT | −0.001 ± 0.003 | 0.001 ± 0.002 | ||
| C13S320 | FLT1 | −0.001 ± 0.005 | 0.002 ± 0.002 | ||
| C1S3181 | ELAVL4 | * | 0.002 ± 0.002 | ||
| C4S1890 | KDR | * | 0.001 ± 0.002 | ||
| C14S1734 | HIF1A | * | 0.001 ± 0.002 | ||
| Q2 | C10S3109 | SIRT1 | 0.104 ± 0.037 | 0.017 ± 0.012 | |
| C9S444 | VLDLR | 0.058 ± 0.022 | 0.012 ± 0.009 | ||
| C8S442 | LPL | 0.008 ± 0.010 | 0.026 ± 0.014 | ||
| C17S1045 | SREBF1 | 0.008 ± 0.012 | 0.004 ± 0.006 | ||
| C6S5380 | VNN1 | 0.005 ± 0.012 | 0.025 ± 0.014 | ||
| C17S1043 | SREBF1 | 0.005 ± 0.008 | 0.013 ± 0.010 | ||
| C6S5441 | VNN3 | 0.003 ± 0.008 | 0.014 ± 0.009 | ||
| C17S1024 | SREBF1 | 0.003 ± 0.007 | 0.003 ± 0.004 | ||
| C11S5292 | PDGFD | 0.002 ± 0.005 | 0.003 ± 0.004 | ||
| C6S5449 | VNN3 | 0.001 ± 0.006 | 0.006 ± 0.006 | ||
| C6S5378 | VNN1 | 0.001 ± 0.005 | 0.005 ± 0.005 | ||
| C9S376 | VLDLR | 0.000 ± 0.007 | 0.009 ± 0.009 | ||
| C3S4880 | BCHE | 0.000 ± 0.003 | 0.004 ± 0.004 | ||
| C10S3093 | SIRT1 | 0.000 ± 0.004 | 0.002 ± 0.002 | ||
| C6S5426 | VNN3 | 0.000 ± 0.005 | 0.002 ± 0.003 | ||
| C2S354 | GCKR | 0.000 ± 0.003 | 0.002 ± 0.002 | ||
| C6S5439 | VNN3 | 0.000 ± 0.003 | 0.001 ± 0.002 | ||
| C3S4874 | BCHE | −0.001 ± 0.003 | 0.006 ± 0.006 | ||
| C8S476 | LPL | −0.001 ± 0.004 | 0.003 ± 0.003 | ||
| C3S4834 | BCHE | −0.001 ± 0.003 | 0.001 ± 0.002 | ||
| C8S1811 | PLAT | −0.001 ± 0.005 | 0.002 ± 0.003 | ||
| C10S3050 | SIRT1 | −0.002 ± 0.006 | 0.004 ± 0.004 | ||
| C3S4856 | BCHE | * | 0.001 ± 0.002 | ||
| C8S1773 | PLAT | * | 0.002 ± 0.003 | ||
| C10S3108 | SIRT1 | * | 0.002 ± 0.002 | ||
| C12S181 | VWF | * | 0.002 ± 0.003 | ||
| C12S211 | VWF | * | 0.002 ± 0.003 | ||
| C17S1009 | SREBF1 | * | 0.002 ± 0.002 | ||
| C17S1048 | SREBF1 | * | 0.001 ± 0.002 |
*
Insufficient variation to calculate the locus-specific heritability.