Table 1.
Sensitivity of Streptomyces Strains Against Plumbagin, Hydrogen Peroxide, and Cumene Hydroperoxide
| |
Zone of inhibition (mm)a |
|||
|---|---|---|---|---|
| Streptomyces reticuli | Streptomyces lividans transformants | |||
| Redox-cycling compound | Wild type | cpeB mutant | pWKS13 (cpeB+) | pWHM3 (cpeB−) |
| Plumbagin (50 mM) | 18 | 27 | 12 | 22 |
| Plumbagin (100 mM) | 24 | 34 | 18 | 34 |
| H2O2 (0.25%) | 0 | 30 | 0 | 20 |
| H2O2 (0. 5%) | 20 | 50 | 5 | 36 |
| CHP (0.25%) | 0 | 10 | 0 | 8 |
| CHP (0.5%) | 0 | 20 | 0 | 14 |
a
Assays were repeated four times.
CHP, cumene hydrogen peroxide; H2O2, hydrogen peroxide.