Table 5.

Additive effects of t-PA dose and other factors on hemorrhage.

		t-PA	n	No hemor- rhage	0-25 ml	>25 ml	p
	N			48	10	8
Platelet count	t-PA dose >50mg	Platelet count <200K/µL	9	4 (44%)	2 (22%)	3 (33%)	0.255
		Platelet count ≥200K/µL	19	14 (74%)	3 (16%)	2 (10%)
	t-PA dose ≤ 50mg	Platelet count <200K/µL	14	10 (71 %)	1 (7.1%)	3 (21.4%)	0.065
		Platelet count ≥200K/µL	25	20 (80%)	5 (20%)	0
Pial collateral	t-PA dose > 50mg	Poor pial collaterals	5	0	2 (40%)	3 (60%)	0.0030
		Good pial collaterals	23	18 (78%)	3 (13%)	2 (8.7%)
	t-PA dose ≤ 50mg	Poor pial collaterals	12	7 (58%)	2 (17%)	3 (25%)	0.023
		Good pial collaterals	27	23 (85%)	4 (15%)	0
Reperfusion	t-PA dose >50mg	Poor reperfusion	12	7 (58%)	1 (8.3%)	4 (33%)	0.135
		Good reperfusion	16	11 (69%)	4 (25%)	1 (6.2%)
	t-PA dose ≤ 50mg	Poor reperfusion	14	8 (57%)	3 (21%)	3 (21%)	0.030.
		Good reperfusion	25	22 (88%)	3 (12%)	0
* Pearson χ2; Bonferroni correction for multiple tests requires p < .0083 for significance