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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Stroke. 2011 Aug 18;42(9):2605–2610. doi: 10.1161/STROKEAHA.110.607101

Figure 3.

Figure 3

Effect of CO on Nrf2-ARE binding activity. (A) Nrf2-ARE binding activity was substantially increased from 0 to 6 hours after 18-hour CO exposure. As a positive control (PC), cultured mouse neurons were treated with the Nrf2 activator sulforaphane (0.5 μM) for 24 hours. (B) Competition with excess nonradioactive probes markedly suppressed Nrf2-ARE binding, but mutant probes were unable to disrupt this binding. CP, cold probe without 32P; MP, mutant probe with 32P.