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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Jan 5;22(4):1565–1568. doi: 10.1016/j.bmcl.2011.12.132

Table 2.

Anti-HIV-1 Activity (EC50) and cytotoxicity (CC50), μMa

graphic file with name nihms348434u6.jpg
Compound Linker EC50 CC50
6a OCH2CH2O 0.390 42
6b OCH2CH2CH2O 0.170 21
6c OCH2CH2CH2CH2O NA >100
6d OCH2CH2OCH2CH2O NA >100
6e NHCH2CH2NH NA 6.0
6f NHCH2CH2CH2NH NA 50
a

NA = not active.