TABLE 1.
Characteristics of subjects who received cholecalciferol and calcium and subjects who received double placebo at the time of enrollment1
| Vitamin D and calcium (n = 30) | Placebo (n = 29) | P2 | |
| Age (y) | 10.2 ± 2.83 | 11.0 ± 2.3 | 0.29 |
| Weight (kg) | 38.0 ± 10.8 | 42.9 ± 12.1 | 0.12 |
| Weight-for-age (percentile) | 56.6 ± 28.9 | 67.6 ± 28.2 | 0.15 |
| Height (cm) | 142 ± 16 | 145 ± 13 | 0.47 |
| Height-for-age (percentile) | 47.8 ± 24.5 | 52.2 ± 30.0 | 0.55 |
| BMI (kg/m2) | 19.5 ± 5.7 | 20.2 ± 3.7 | 0.61 |
| BMI (percentile) | 59.2 ± 29.4 | 71.9 ± 24.9 | 0.09 |
| Male sex [n (%)] | 13 (43) | 13 (45) | 0.91 |
| Black [n (%)] | 18 (60) | 20 (69) | 0.48 |
| Hispanic [n (%)] | 12 (40) | 10 (34) | 0.67 |
| Tanner stage [n (%)] | 0.48 | ||
| 1–2 | 17 (56.7) | 12 (41.4) | |
| 3–4 | 9 (30.0) | 10 (34.5) | |
| ≥5 | 4 (13.3) | 7 (24.1) | |
| Antiretroviral medications [n (%)] | 0.27 | ||
| None | 0 (0.0) | 1 (3.5) | |
| RTIs only | 8 (26.7) | 3 (10.3) | |
| NNRTI containing | 7 (23.3) | 4 (13.8) | |
| PI containing | 10 (33.3) | 15 (51.7) | |
| NNRTI + PI containing | 5 (16.7) | 6 (20.7) | |
| CD4 (%) | 31.7 ± 11.8 | 30.2 ± 10.2 | 0.63 |
| CD4 count (cells/mm3) | 800 ± 377 | 759 ± 387 | 0.68 |
| CD4 >500 cells/mm3 [n (%)] | 24 (80) | 21 (72) | 0.50 |
| CDC class [n (%)] | 0.71 | ||
| A | 13 (43) | 10 (34) | |
| B | 12 (40) | 12 (42) | |
| C | 5 (17) | 7 (24) | |
| Viral load log10 (RNA copies/mL) | 2.7 ± 1.0 | 2.9 ± 1.1 | 0.48 |
| Viral load > level of detection [n (%)] | 16 (53) | 19 (66) | 0.35 |
| Sunlight exposure (h/wk) | 10.4 ± 12.2 | 7.9 ± 7.2 | 0.49 |
| Dietary calcium (mg/d) | 657 ± 290 | 654 ± 302 | 0.98 |
| Dietary calcium (% of RDA) | −34.3 ± 29.1 | −34.6 ± 30.2 | 0.98 |
| Dietary vitamin D (IU/d) | 148 ± 84 | 147 ± 85 | 0.97 |
| Dietary vitamin D (% of RDA) | −63.0 ± 21.0 | −63.3 ± 21.2 | 0.97 |
| Serum 25(OH)D (ng/mL) | 24.1 ± 9.1 | 23.6 ± 10.2 | 0.87 |
| Serum 25(OH)D between 12 and 20 ng/mL [n (%)] | 11 (37) | 10 (34) | 0.70 |
1
NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor; RDA, Recommended Dietary Allowance; RTI, reverse transcriptase inhibitor; 25(OH)D, 25-hydroxyvitamin D.
2
For Student's t test or Fisher's exact test.
2
Mean ± SD (all such values).