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. 2012 Jan 11;11:7. doi: 10.1186/1475-2859-11-7

Table 2.

Yields of o-chloroacetophenone reductions catalyzed by E. coli whole-cell biocatalysts variable in XR and FDH activities.

E coli pH XR (U/gCDW) FDH (U/gCDW) Substrate (mM) Yield (mM)1 Yield (mM)1, 2
BL21_XR_FDH 7.5 1406 110 100 19 46

Rosetta_XR_2FDH 7.5 1140 251 100 35 67

BL21_XR_FDH 6.2 2226 48 100 27 78

Rosetta_XR_2FDH 6.2 2024 189 100 63 95

1Determined for a reaction time of 8 h. 2Additives: 36 μM Polymyxin B sulphate and 500 μM NAD+.