Table 2.
Phage ID | Peptide | Abundance a | |
---|---|---|---|
Patient 1 (MS 02-24) | MS-1 CSF #1-A6b | S F G T F L W | 80% (4/5) |
MS-1 CSF #1-B1 | E F G T F L W c | 20% (1/5) | |
MS-1 CSF #2-C7 | E F G T F L W | 36% (4/11) | |
MS-1 CSF #2-C9 | K F G T A L W | 27% (3/11) | |
MS-1 CSF #2-C5 | Q F G T F L W | 27% (3/11) | |
MS-1 CSF #2-D7 | S F G T A L W | 9% (1/11) | |
| |||
Patient 2 (MS 04-3) | MS-2 CSF #1-B1 | V L N W H P F | 100% (8/8) |
MS-2 CSF #2-C9 | V L N W H P F | 50% (1/2) | |
MS-2 CSF #2-C6 | M F N W H P F | 50% (1/2) | |
| |||
Patient 3 (MS 05-4) | MS-3 CSF #1-A1 | W G L D N P P | 33% (2/6) |
MS-3 CSF #1-A2 | A P P H L P P | 17% (1/6) | |
MS-3 CSF #1-E7 | A P S H P P P | 17% (1/6) | |
MS-3 CSF #1-A6 | A P P H Q M P | 17% (1/6) | |
MS-3 CSF #1-A12 | T Y M V P A P | 17% (1/6) | |
MS-3 CSF #2-D9 | W G L D N P P | 56% (5/9) | |
MS-3 CSF #2-F10 | A P A H Q I P | 11% (1/9) | |
MS-3 CSF #2-B11 | A P A H H P P | 11% (1/9) | |
MS-3 CSF #2-B10 | A P P H V M P | 11% (1/9) | |
MS-3 CSF #2-C11 | G P V N M N L | 11% (1/9) | |
| |||
Patient 4 (MS 05-6) | MS-4 CSF #1-E12 | F H L P W M Q | 100% (1/1) |
MS-4 CSF#2-H4 | W Y Y K P P A | 60% (3/6) | |
MS-4 CSF #2-D10 | K W P I I D T | 20% (1/5) | |
MS-4 CSF #2-G9 | F H L P W M Q | 20% (1/5) | |
| |||
Patient 5 (ON 05-2) | MS-5 CSF #1-E9 | c P V E L Q L Y c | 17% (1/6) |
MS-5 CSF #1-A9 | c S Q S V AA S c | 17% (1/6) | |
MS-5 CSF #1-E8 | c G R Q A Q Y Y c | 17% (1/6) | |
MS-5 CSF #1-C10 | c P V G P W T N c | 17% (1/6) | |
MS-5 CSF #1-C9 | c T V Q P Q F H c | 17% (1/6) | |
MS-5 CSF #1-F9 | c M Q A H Q T K c | 17% (1/6) | |
MS-5 CSF #2-F12 | c P L E L S V Y c | 60% (3/5) | |
MS-5 CSF #2-H11 | c S H R P T T Q c | 20% (1/5) | |
MS-5 CSF #2-C12 | c S T E G R H N c | 20% (1/5) |
Positive phage were amplified, purified, and phage DNA was sequenced. Peptides are listed in order of their relative frequencies of the total clones sequenced.
Each phage peptide was named by panning CSF IgG (patient # and CSF #) followed by the location of the well from which the phage was initially identified. For example, peptide MS-1 CSF #1-A6 indicates that the phage was selected by CSF IgG of patient 1 and CSF 1 from well A6.
The identical/similar peptides were highlighted.
Circular peptides.