Figure 1. Phenotype of CD127+132−, CD127+132+ and CD127−132+ T-cells based on extracellular expression of CCR7 and CD45RO in a) health and b) chronic HIV infection (representative raw data).

Data collected from thawed cryopreserved peripheral blood mononuclear cells (PBMCS) are shown. Cells were initially gated on CD3 vs side-scatter histograms to isolate lymphocytes before being plotted on CD3 vs CD4 histogram to separate CD4+ (ii–iv) and CD8+ (v–viii) lymphocytes (via negative CD4 gating). Data representative of 20 subjects are shown.