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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Int J Neuropsychopharmacol. 2011 Sep 12;15(8):1135–1148. doi: 10.1017/S1461145711001386

Fig. 4.

Fig. 4

D-Serine improved measures of helplessness and sexual reward-seeking deficits in wild-type (WT) mice that developed helplessness. (a) D-Serine treatment significantly reduced escape latencies in male WT mice that developed helplessness, (b) increased the number of escapes, and (c) increased the number of mice that recovered from helplessness. (d) D-Serine treatment significantly increased sniffing duration in learned helplessness (LH) mice vs. saline-treated LH mice. Data are mean±S.E.M. (* p<0.05, *** p<0.001).