Figure 6. Effect of blocking MAB to GM-CSF, IFNγ, TNF- α on SP induced monocyte TF expression.
In order to determine if the effect of SP on monocyte TF expression was direct or indirect through the cytokine pathway, monocytes were stimulated with SP in the presence or absence of blocking MAB to GM-CSF, IFN γ, and TNF Effects of SP and GM-CSF, IFN-γ and TNF-α alone, with all controls are shown. The data are the mean ± SEM of triplicate and are representative of three experiments. p<0.005, 0.0001 and 0.01 represents significant as indicated.