Table 3.

Porosity measured with synchrotron high-resolution CT in ROIs near the endosteal surface (Endo), intracortically (Intra), and near the periosteal surface (Peri).

Endo	Ctrl	OVX	ALN	PTH
Lc.N/TV [mm−3]	43,370 (15,480)O	61,500 (7,410)C,A	48,030 (17,330)O	62,480 (16,840)
Lc.V/TV [%]	1.40 (0.44)	1.40 (0.22)	1.05 (0.49)P	1.50 (0.40)A
<Lc.V> [mm3]	284.9 (98.9)O	238.0 (14.1)C,P	256.0 (60.4)	285.6 (37.9)O
Ca.V/TV [%]	0.77 (0.45)	0.90 (0.10)	0.92 (0.81)	1.53 (1.25)
% porosity	2.36 (0.53)	2.29 (0.18)P	2.17 (1.02)P	3.33 (1.52)O,A
Sm.N/TV [mm−3]	13,450 (5,830)	10,950 (2,369)	8,608 (6,062)P	14,650 (31,100)A
Intra
Lc.N/TV [mm−3]	65,250 (15,020)	73,000 (7,840)A	63,990 (10,550)O	66,580 (16,520)
Lc.V/TV [%]	1.51 (0.64)	1.79 (0.34)A	1.39 (0.39)O	1.59 (0.50)
<Lc.V> [mm3]	272.1 (32.2)	258.0 (26.3)	230.7 (49.2)	258.5 (23.0)
Ca.V/TV [%]	0.94 (0.31)	0.88 (0.21)	0.97 (0.63)	0.98 (0.64)
% porosity	2.74 (0.66)	2.77 (0.33)	2.38 (0.63)	2.36 (0.98)
Sm.N/TV [mm−3]	16,410 (19,730)	16,000 (8,340)	12,870 (4,720)	20,610 (27,430)
Peri
Lc.N/TV [mm−3]	47,000 (8,430)	49,500 (12,830)	64,020 (10,290)	57,400 (27,870)
Lc.V/TV [%]	1.45 (0.15)	1.51 (0.44)	1.63 (0.25)	1.74 (0.52)
<Lc.V> [mm3]	302.6 (71.3)	317.5 (51.7)A	261.5 (46)O	273.2 (72.3)
Ca.V/TV [%]	0.41 (0.29)	0.32 (0.23)A	0.80 (0.32)O	0.77 (0.88)
% porosity	1.89 (0.19)	1.84 (0.64)p	2.45 (0.51)	2.53 (0.99)o
Sm.N/TV [mm−3]	19,210 (17,990)	17,050 (25,480)	19,110 (14,120)	24,540 (16,430)

Data are represented as median (interquartile range). A Mann-Whitney test was performed between Ctrl and OVX. A Kruskal-Wallis test was performed between OVX, ALN, and PTH. For each parameter that showed a significant difference with Kruskal-Wallis (p < 0.05), a Mann-Whitney test was performed to test for differences between specific groups.

^Cdifferent from Ctrl (p < 0.01).

^Odifferent from OVX (p < 0.01).

^odifferent from OVX (p < 0.05).

^Adifferent from ALN (p < 0.01).

^Pdifferent from PTH (p < 0.01).

^pdifferent from PTH (p <0.05).