Table 2.
Characteristics of Adults with Non-NASH Histology by Race and Ethnicity
| Total Population (N=398) | Non Latino Black (N=13) | Non Latino White (N=302) | Latino (N=44) | Asian (N=26) | Other (N=13) | p- value‡ | |
|---|---|---|---|---|---|---|---|
| Age (years)* | 46.9 (45.8–48.1) | 51.6 (44.3–58.9) | 48.4 (47.1–49.6) | 38.0 (34.0–42.0) | 43.3 (38.2–48.4) | 47.1 (40.9–53.2) | <0.0001 |
| Gender (%male)# | 176 (44) | 1 (8) | 129 (43) | 23 (52) | 17 (65) | 6 (46) | 0.26 |
| BMI (kg/m2)* | 33.8 (33.2–34.4) | 38.1 (34.5–41.7) | 34.1 (33.4–34.8) | 33.7 (31.7–35.6) | 27.4 (25.8–29.0) | 35.4 (32.0–38.7) | 0.68 |
| Waist (cm)* | 107.3 (105.9–108.6) | 111.0 (104.7–117.3) | 108.2 (106.6–109.7) | 108.0 (103.2–112.8) | 92.3 (87.7–96.9) | 110.5 (103.8–117.3) | 0.90 |
| ALT (U/L)** | 57 (53–59) | 33 (22–57) | 56 (49–58) | 60 (51–75) | 69 (56–85) | 67 (39–123) | 0.26 |
| AST (U/L)** | 36 (33–38) | 27 (22–41) | 36 (33–39) | 34 (31–42) | 39 (32–44) | 60 (29–68) | 0.94 |
| GGT (U/L)** | 40 (36–42) | 34 (28–49) | 39 (35–42) | 38 (31–45) | 57 (41–126) | 38 (23–60) | 0.63 |
| Albumin (g/L)** | 4.3 (4.2–4.3) | 4.3 (4.0–4.4) | 4.3 (4.2–4.3) | 4.2 (4.1–4.3) | 4.5 (4.3–4.6) | 4.5 (4.2–4.8) | 0.15 |
| Total bilirubin (mg/dL)** | 0.7 (0.7–0.7) | 0.5 (0.2–0.7) | 0.7 (0.7–0.7) | 0.7 (0.6–0.9) | 0.9 (0.7–1.1) | 0.6 (0.4–0.8) | 0.53 |
| Alkaline phosphatase (U/L)** | 77 (74–79) | 99 (70–117) | 78 (75–80) | 72 (64–82) | 70 (63–87) | 86 (57–99) | 0.27 |
| Platelets (x 103) ** | 252 (246–259) | 283 (249–359) | 250 (245–258) | 252 (227–283) | 243 (204–277) | 258 (223–329) | 0.85 |
| Total cholesterol (mg/dL)** | 195 (191–200) | 202 (171–234) | 196 (192–202) | 181 (167–197) | 202 (180–209) | 190 (157–229) | 0.02 |
| Triglyceride (mg/dL)** | 147 (135–158) | 102 (64–172) | 151 (137–162) | 122 (103–147) | 178 (125–225) | 141 (97–218) | 0.06 |
| HDL (mg/dL)** | 43 (41–44) | 58 (41–65) | 43 (42–45) | 39 (35–42) | 41 (36–49) | 40 (32–47) | 0.03 |
| LDL (mg/dL)** | 120 (117–125) | 138 (98–162) | 121 (118–126) | 113 (105–132) | 112 (102–122) | 128 (92–151) | 0.39 |
| Systolic BP (mmHg)** | 131 (129–133) | 140 (121–152) | 132 (130–134) | 128 (123–133) | 124 (115–130) | 140 (124–146) | 0.28 |
| Diastolic BP (mmHg)** | 77 (75–78) | 77 (75–86) | 77 (76–79) | 76 (71–78) | 71 (68–75) | 83 (77–88) | 0.17 |
| Hypertension (%)# | 226 (57) | 10 (77) | 178 (59) | 15 (34) | 13 (50) | 10 (77) | 0.003 |
| Diabetes mellitus (%)# | 78 (20) | 7 (54) | 55 (18) | 3 (7) | 9 (35) | 4 (31) | 0.08 |
| Fasting Glucose (mg/dL)** | 95 (93.0–97.0) | 108 (86.3–144.7) | 94 (92.5–96.0) | 92 (86.1–95.0) | 101 (92.5–110.0) | 99 (88.4–156.0) | 0.66 |
| Fasting Insulin (microU/L)** | 15.2 (14.0–16.0) | 20.2 (14.2–38.7) | 14.0 (13.0–15.4) | 20.0 (16.6–30.8) | 14.5 (10.6–21.5) | 17.9 (7.7–26.6) | <0.0001 |
| HOMA-IR** | 3.5 (3.2–3.8) | 5.0 (2.7–10.4) | 3.2 (2.9–3.5) | 5.0 (3.7–6.9) | 3.8 (2.6–5.5) | 5.1 (1.6–8.2) | 0.0002 |
| Hyperlipidemia (%)# | 310 (78) | 9 (69) | 241 (80) | 29 (66) | 21 (81) | 10 (77) | 0.05 |
| Metabolic syndrome (%)# | 270 (68) | 9 (69) | 212 (70) | 24 (55) | 15 (58) | 10 (77) | 0.06 |
| Family history of NAFLD (%)# | 30 (8) | 0 (0) | 21 (7) | 7 (16) | 1 (4) | 1 (8) | 0.07 |
| Acanthosis nigricans (%)# | 47 (12) | 6 (46) | 23 (8) | 13 (30) | 2 (8) | 3 (23) | <0.001 |
| Palmar erythema (%)# | 33 (8) | 1 (8) | 30 (10) | 1 (2) | 0 (0) | 1 (8) | 0.15 |
| Education (> HS)# | 294 (74) | 8 (62) | 231 (76) | 23 (52) | 22 (85) | 10 (77) | 0.002 |
| Income (>$50,000)# | 258 (65) | 4 (31) | 206 (68) | 20 (45) | 20 (77) | 8 (62) | 0.004 |
| Total caloric intake (kcal)** | 1710 (1608–1799) | 1435 (822–2755) | 1732 (1635–1822) | 1801 (1434–2222) | 1230 (1002–1722) | 1778 (1238–2394) | 0.85 |
| % Calories from fat** | 38.9 (38.0–39.9) | 37.0 (32.3–44.3) | 39.6 (38.3–40.4) | 36.8 (34.0–39.7) | 39.2 (32.0–43.5) | 38.1 (29.4–39.6) | 0.06 |
| %Calories from carbohydrates* * | 46.9 (45.8–47.7) | 52.9 (45.0–58.3) | 46.2 (45.2–47.3) | 48.6 (44.8–51.5) | 45.3 (42.0–56.8) | 49.1 (47.4–58.2) | 0.13 |
| Physical activity (met hrs/week)** | 30.0 (27.6–32.0) | 20.0 (15.8–30.6) | 29.0 (26.0–32.0) | 37.0 (29.1–55.9) | 26.9 (11.5–42.5) | 34.0 (16.5–65.8) | 0.25 |
*
Mean (95% confidence interval)
**
Median (95% confidence interval)
#
N (%)
‡
Comparing Latino and Non-Latino White individuals