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Libraries derived from amides 45.
| Entry | Amide | Electrophile | Product | Yield(%) |
|---|---|---|---|---|
| 1 | 45{1} | 50{1} | 48{1,1} | 80 |
| 2 | 45{1} | 50{2} | 48{1,2} | 86 |
| 3 | 45{15} | 50{1} | 48{15,1} | 80 |
| 4 | 45{15} | 50{2} | 48{15,2} | 76 |
| 5 | 45{1} | 51 | 49{1} | 72 |
| 6 | 45{13} | 51 | 49{13} | 66 |
| 7 | 45{4} | 51 | 49{4} | Tracea |
| 8 | 45{15} | 51 | 49{15} | 95 |
| 9 | 45{16} | 51 | 49{16} | 85 |
| 10 | 45{7} | 51 | 49{7} | 44 |
| 11 | 45{10} | 51 | 49{10} | 91 |
| 12 | 45{17} | 51 | 49{17} | 0 |
Trace formation of the pyrrole product 49{4} was observed in the 1H NMR spectrum of the crude reaction mixture.
