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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Invest Dermatol. 2011 Nov 24;132(3 0 1):609–614. doi: 10.1038/jid.2011.385

Figure 1. Direct visualization of macromolecule endocytosis by epidermal LCs.

Figure 1

Anesthetized wild-type BALB/c mice received s.c. injection of 70 kDa FITC-DX probes into ear skin. At 0 (panel a), 24 (b), and 48 hours (c) after the injection, the mice were placed under a confocal microscope to record FITC fluorescence signals in the ear skin. Data shown are compiled x-y plane fluorescence images in the indicated z-axis depth ranges from the skin surface, i.e., Stratum corneum. Scale bar: 200 μm.