Table 1.

Ile-, Val-, and Thr-rich potential amyloid sequences from yeast and mammalian CAMs^a

	Accession number	Sequence	Position in ORFb	TANGO β-aggregate %c	%IVTd
Yeast proteins
C. albicans Alsl Als3, Als5	EAK99144, EAK93472, EAK99139	IVIVATT	325	93	83
S. cerevisiae Flo1	AAC09499	TVIVI	308, 1547	43	100
S. cerevisiae Flo11	NP_012284	VVSTTV	1036, 1367	75	83
Mammalian proteins
Integrin α4	NP 000876	VFVYI	340	94	60
		YIVLFY	502	69	33
N-CAM	AAB31836	IVTIVGL	660	98	71
e-Cadherin	CAA78353.1	VGVFII	202	98	67
		VISVVTT	325	83	87
		VVITTL	391	62	83
Galectin 4	AAP35679.1	LVFIVLA	103	99	43
Galectin 12	EAW74155.1	YVTTIF	49	99	67
SigLec	AAF34702.1	SVFVTAL	146	87	43

^aMore extensive lists of such sequences for other Als proteins and other yeast adhesins have been published [14-16].

^bORF denotes open reading frame.

^cβ-Aggregate potential of the designated sequence according to the predictor TANGO [15, 49].

^dIVT indicates percent of Ile + Val + Thr in the designated sequence.