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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Pharmacol Res. 2011 Dec 1;65(3):338–346. doi: 10.1016/j.phrs.2011.11.013

Figure 3.

Figure 3

Antagonism by MRS1523 of the effects of 6 on cardiomyocytes subjected to hypoxia. Cardiomyocytes were treated with 6 (1 nM) and exposed to hypoxia (H). (A) LDH released to the medium was determined immediately after hypoxia. 100% activity was the total LDH activity in homogenate of untreated cells. (B) Percent of dead cells determined by PI staining. 100% is the number of cells in each well. *P<0.001 compared to normoxia. **P<0.001 compared to hypoxia. #P<0.05 compared to hypoxia.