Infarct size limiting effects of dendrimers on isolated hearts in the Langendorff system subjected to ischemia. Isolated rat hearts were treated with 1 or 2 at concentrations of 10 or 100 pM, and exposed to ischemia (I). A. Damaged area calculated by Image Pro 5.1 Plus of infarct size of slices of hearts stained by TTC and exposed to: ischemia (B), 2 (100 pM) before the ischemia (C), 2 (10 pM) before the ischemia (D), 1 (100 pM) before the ischemia (E), 1 (10 pM) before the ischemia (F). *P<0.001 compared to ischemia. **P<0.05 compared to ischemia. The scale below the heart is marked in mm units.