Skip to main content
. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Pharmacol Res. 2011 Dec 1;65(3):338–346. doi: 10.1016/j.phrs.2011.11.013

Figure 6.

Figure 6

Physiological effects of dendrimers on isolated hearts in the Langendorff system subjected to ischemia. Isolated rat hearts were treated with 1 or 2 at concentrations of 10 or 100 pM, and exposed to ischemia (I). A. Percent of rate pressure product (RPP) after the ischemia. Preischemic RPP is considered as 100%. (B) Positive dP/dtmax (dP/dt) and (C) negative (ndP/dtmax) ndP/dt before and after the ischemia. Coronary flow (D) is expressed as % of the preischemic value.

*P<0.05 compared to ischemia. **P<0.05 compared to non-treated hearts 30 min after the end of ischemia. #P<0.05 compared to before ischemia.