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. Author manuscript; available in PMC: 2013 Feb 21.
Published in final edited form as: Vaccine. 2011 Dec 15;30(9):1737–1745. doi: 10.1016/j.vaccine.2011.12.026

Fig. 3. Polyfunctionality of elicited CD4 and CD8 T cells at peak vaccine response and 2 weeks post infection.

Fig. 3

Intracellular cytokine staining was used to test for patterns of IFN-γ (I), IL-2 (L) and TNF-α (T) production in peptide stimulated cells. Peak vaccine responses (left column) were analyzed for the DDMM regimen after the 1st MVA boost; and for the MMM regimen, after the 2nd MVA inoculation. The right column displays responses at 2 weeks post infection. Responses for the DDMM regimen are in turquoise; for the MMM regimen, in fuchsia and for unvaccinated controls, in white. Boxplots present medians and interquartile ranges. In (D), for the DDMM regimen, medians and interquartile range represent data for a sample size of 2. * is used to indicate p<0.05; **, p<0.01; and ***, p<0.001.