Fig. 6. Post infection immune responses.
(A) Temporal IFN-γ producing CD4 T cell responses, (B) Temporal IFN-γ producing CD8 T cell responses, (C) Temporal Env-specific IgG responses in blood and (D) Temporal Env-specific IgA responses in rectal secretions. T cell responses are the sum of responses to Gag and Env. Responses in DDMM-vaccinated animals are in turquoise, those in MMM vaccinated animals, in fuchsia, and those for unvaccinated animals, in black. The plots of responses start with a week 48 prechallenge response. Responses have been displaced by ½ week to better allow visualization of the different curves: DDMM is plotted at −0.5 weeks, MMM at the actual week and unvaccinated at +0.5 weeks. In (D), the grey box represents the level below which responses are not considered significant. * is used to indicate p<0.05; **, p<0.01; and ***, p<0.001.
