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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Mol Cell Neurosci. 2011 Dec 4;49(2):171–183. doi: 10.1016/j.mcn.2011.11.007

Figure 8. Pten deletion disrupts proper retinal function.

Figure 8

(A, B) Representative scotopic (A) and photopic (B) ERGs at different light intensities from control (black trace) and Pten mutant (blue trace) mice.

(C, D) Amplitudes of a-wave (C) and b-wave (D) for scotopic and photopic ERGs. Pten mutants show significantly decreased scotopic a-wave and b-wave amplitudes (Individual animals tested (n) are indicated. Mean ± S.E.M. *, p<0.05).

(E–H) Comparison of oscillatory potential waveforms and amplitudes. Pten mutants show similar OPs as controls under dark-adapted conditions (E, F), but enhanced OP amplitudes after light adaptation (G, H) (Individual animals tested (n) are indicated. Mean ± S.E.M. **, p<0.01; *, p<0.05).