Figure 1.
The time course of contextual and cued fear conditioning after nicotine withdrawal. A) Contextual fear conditioning was examined 1-8, and 16 days after cessation of nicotine treatment; deficits in learning were seen on days 1-4. B) Cued fear conditioning was examined 1-8, and 16 days after cessation of nicotine treatment; no deficits were seen. All time points are separate groups of mice. * = significant difference from saline (n=7-13). Data are presented as mean and standard error of the mean.