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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Neuropharmacology. 2012 Jan 21;62(5-6):2118–2125. doi: 10.1016/j.neuropharm.2012.01.003

Table 2.

Cerebellar and cortical cytisine-sensitive and cytisine-resistant nAChR binding data

Cerebellum Hours After Withdrawa1

Cytisine Sensitive 0 24 hrs 48hrs 72hrs 96hrs 120 hrs 144 hrs
Saline 13.80 15.59 15.17 12.95 10.49 10.84 13.48
Standard Error 1.24 1.29 1.27 0.73 1.73 1.09 0.92
Nicotine 21.71 * 18.29 18. 16 13.47 16.65 * 14.19 15.30
Standard Error 0.94 * 1.10 1.24 0.60 1.49 * 1.56 0.89

Cytisine Resistant 0 24hrs 48hrs 72hrs 96hrs 120 hrs 144 hrs

Saline 4.09 4.89 4.72 4.14 5.24 5.50 5.50
Standard Error 0.18 0.21 0.20 0.23 0.26 0.29 0.28

Nicotine 4.88 4.62 5.47 4.11 5.86 5.93 5.45
Standard Error 0.33 0.47 0.31 0.13 0.53 0.31 0.26
Cortex Hours After Withdrawa1

Cytisine Sensitive 0 24hrs 48hrs 72hrs 96hrs 120 hrs 144 hrs
Saline 36.26 34.81 37.03 35.35 26. 87 39.61 36.90
Standard Error 3.90 4.13 6.16 4.86 3.59 4.19 2.74
Nicotine 49.17 40.78 46.34 51.85* 38.82 40.93 32.45
Standard Error 4.84 1.34 4.49 3,79* 4.46 6.06 5.95

Cytisine Resistant 0 24hrs 48hrs 72hrs 96 hrs 120 hrs 144 hrs

Saline 4.15 4.43 3.87 4.16 3.86 4.15 3.77
Standard Error 0.27 0.32 0.21 0.19 0.23 0.38 0.16
Nicotine 5.76 * 5.13 4.99 5.65 * 4.99 4.25 4.17
Standard Error 0.43 * 0.47 0.50 0.73 * 0.24 0.45 0.29
*

Indicates significant difference between nicotine and saline. Data presented as mean and standard error of the mean.