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Hearing thresholds in 29 females (a) and 29 males (b) with Pompe disease stratified by age. The shaded area represents the 95 percent confidence interval for normal hearing (ISO 8253–1). The connected lines represent the pure-tone audiograms of the individual patients for the right and left ear; each patient within an age group is represented by a different symbol (×, △, ▲, ▽, ▼, ◆, ◇, ●, ○, ■, or □)
