Table II.
Variable | Hazard ratio | p† | p‡ |
---|---|---|---|
Response to first line therapy (refractory vs relapsed) |
0.57 | 0.04 | 0.007 |
Risk factors prior to salvage therapy (3 vs 0) |
1.97 | 0.23 | |
Response to ICE (CR vs PR, MR) |
1.27 | 0.52 | |
Conditioning regimen (TLI vs no TLI) |
0.92 | 0.78 | |
Time to HDT-ASCT failure | |||
After 6 months | 0.49 | 0.01 | 0.06 |
After 12 months | 0.48 | 0.06 | |
Regimens following HDT- ASCT failure |
|||
Gemcitabine-based | 1.31 | 0.34 | |
MOPP | 0.98 | 0.96 | |
Radiation | 0.67 | 0.27 | |
Second transplant | 2.26 | 0.009 | 0.004 |
Univariate analysis
Multivariate analysis