Table 1.
Variables | Belatacept n = 27 | CsA n = 9 | P value |
---|---|---|---|
Donor's age (years); mean ± s.d. | 33·8 ± 11·2 | 29·8 ± 9·6 | n.s. |
Female donor, n (%) | 12 (44·4) | 4 (44·4) | n.s. |
Living donor, n (%) | 23 (85·2) | 8 (88·9) | n.s. |
Donor pre-implantation cGFR (MDRD) (ml/min); mean ± s.d. | 100·7 ± 23·9 | 108·2 ± 17·8 | n.s. |
Recipient age (years); mean ± s.d. | 32·1 ± 10·2 | 30·8 ± 11·7 | n.s. |
Female recipient, n (%) | 11 (40·7) | 3 (33·3) | n.s. |
PRA (%) | 1·81 (0–37) | 1·08 (0–27) | n.s. |
Acute rejection during 1st year | 2 (Banff IA, Banff III) | 1 (Banff IA) | n.s. |
Borderline | 0 | 1 | |
Recipient cGFR (MDRD) at 1 month (ml/min); mean ± s.d. | 70·9 ± 21·2 | 76·8 ± 15·8 | n.s. |
Recipient cGFR (MDRD) at 12 months (ml/min); mean ± s.d. | 77·9 ± 29·7 | 69·8 ± 18·0 | n.s. |
Δ cGFR (MDRD) [12–1 months] (ml/min); mean ± s.d. | 6·2 ± 17·2 | −6·2 ± 20·3 | 0·029 |
CsA: cyclosporin A; cGFR: glomerular filtration rate calculated by modification of diet in renal disease (MDRD) formula; PRA: panel-reactive antibodies; s.d.: standard deviation; n.s.: not significant.