Table 1.
Incidence of the p16 CpG Island Methylation in the Different Lymphoma Subtypes
| Subtype | n | Total (%) | At diagnosis (%) | At relapse (%) | ||
|---|---|---|---|---|---|---|
| CD30 NHL | ||||||
| ALCL | Null | 12 | 6 (50) | 4/9 (44) | 2/3 | |
| T cell | 13 | 2 (15) | 2/10 (20) | 0/3 | ||
| PTCL | 13 | 3 (23) | (19) | 3/11 (27) | 0/2 | |
| DLBCL | 15 | 4 (27) | 2/10 (20) | 2/5 | ||
| Total NHL | 53 | 15 (28) | 11/40 (27) | 4/13 (31) | ||
| HL | 26 | 10 (38) | 5/20 (25) | 5/6 (83) |
n, Number of cases studied; NHL, non-Hodgkin’s lymphomas; ALCL, anaplastic large-cell lymphomas; PTCL, peripheral T cell lymphomas; DLBCL, diffuse large B cell lymphomas; HL, Hodgkin’s lymphomas.