Table 2.
Results of the hemodynamic measurements at the beginning (pre) and at the end of the experiment (post).
| L-IV | L-IC | Control | |
|---|---|---|---|
| CO (l/min) | |||
| Pre | 4.07 ± 0.70 | 3.38 ± 0.37 | 3.23 ± 0.37 |
| Post | 2.28 ± 0.61* | 1.57 ± 0.23* | 2.00 ± 0.35* |
| MAP (mmHg) | |||
| Pre | 61.88 ± 8.71 | 65.88 ± 14.5 | 61.00 ± 8.11 |
| Post | 83.5 ± 17.71* | 85.38 ± 21.82 | 80.25 ± 17.90 |
| HR (/min) | |||
| Pre | 105.13 ± 16.39 | 111 ± 9.99 | 106.13 ± 20.1 |
| Post | 105.5 ± 23.13 | 108.63 ± 12.97 | 105.86 ± 12.9 |
| CVP (mmHg) | |||
| Pre | 3.63 ± 3.70 | 3.13 ± 0.99 | 2.88 ± 0.83 |
| Post | 3.13 ± 3.04 | 4.25 ± 2.05 | 4.38 ± 1.30 |
| PCWP (mmHg) | |||
| Pre | 3.75 ± 3.77 | 4.25 ± 1.67 | 4.38 ± 2.2 |
| Post | 3.13 ± 3.18 | 5.5 ± 4.44 | 3.75 ± 1.16 |
| SVR | |||
| Pre | 14.51 ± 1.48 | 18.67 ± 4.11 | 18.28 ± 3.88 |
| Post | 38.63 ± 9.90* | 51.42 ± 9.38* | 38.95 ± 11.2* |
| Calculated SW | |||
| Pre | 2.49 ± 0.92 | 2.02 ± 0.59 | 1.93 ± 0.52 |
| Post | 1.86 ± 0.93 | 1.25 ± 0.43 | 1.54 ± 0.49 |
Data presented as mean ± SEM. L-IV, levosimendan infusion-group, L-IC, intracoronary levosimendan-group. CO, cardiac out-put; MAP, mean arterial pressure; HR, heart rate; CVP, central venous pressure; PCWP, pulmonary capillary wedge pressure; SVR, systemic vascular resistance, Calculated SW = left ventricle stroke work = (CO/HR) × MAP. *p < 0.05 pre vs. post, p < 0.05 between groups (values in bold).