Table 9.

Toxicity of SAHA standard and modified ligand based on Toxtree v2.1.0.

Ligand	Negatif for genotoxic carcinogenity	Negatif for nongenotoxic carcinogenity	Potential S.Typhiurium TA 100 mutagen based on QSAR	Potential carcinogen based on QSAR
SAHA	yes	yes	no	no
1a	yes	yes	no	no
1b	no	yes	no	no
1c	yes	yes	no	no
1d	yes	no	no	no
1e	yes	yes	no	no
1f	yes	no	no	no
2a	yes	yes	no	no
2b	no	yes	yes	no
2c	yes	yes	no	no
2d	yes	no	no	yes
2e	yes	yes	no	no
2f	yes	no	no	no