Table 3.
Effect of the acute, intraperitoneal administration of different doses of GET73 on a series of variables measured in habituation and test sessions in Sprague-Dawley rats exposed to the Active Avoidance test.
| GET73 (mg/kg) | Habituation session (day 1) | Test session (day 2) |
||
|---|---|---|---|---|
| Number of crossings | Number of avoidances | Number of escapes | Number of escape failures | |
| 0 | 54.5 ± 7.2 | 57.9 ± 3.1 | 31.3 ± 3.8 | 10.9 ± 2.2 |
| 5 | 62.6 ± 9.6 | 38.3 ± 10.1 | 31.9 ± 5.9 | 29.9 ± 11.9 |
| 10 | 83.1 ± 4.3 | 50.6 ± 9.5 | 28.4 ± 4.3 | 21.0 ± 7.1 |
| 25 | 62.9 ± 8.1 | 47.3 ± 8.7 | 33.5 ± 5.1 | 19.3 ± 7.9 |
GET73 was administered acutely 30 min before the test session. Each value is the mean ± SEM of n = 8.