Skip to main content
. 2012 Feb 14;2:264. doi: 10.1038/srep00264

Figure 3. Differential transcript expression between TNBC, Non-TNBC and HER2-positive cancers.

Figure 3

(A) The number of statistically significant differentially expressed transcripts identified from the F-test. Volcano plots show the differential expression of the statistically significant transcripts (p value less than 0.05 and FDR 0.05) between (B) TNBC vs. Non-TNBC (C) TNBC vs. HER2-positive and (D) Non-TNBC vs. HER2 positive pairwise comparisons. The Circos plots show statistically significant differences in transcript expression from the above univariate F-test between (E) TNBC vs. Non-TNBC (F) TNBC vs. HER2-positive and (G) Non-TNBC vs. HER2- positive breast cancers. The top hundred transcripts as determined by the p-value are labelled on the Circos plot. The stacked histograms represent the abundance (FPKM) associated with each sample for that specific differentially expressed transcript. The TNBC group samples A1 to A6 are coloured in red, orange, yellow, green blue and purple. The Non-TNBC group samples B1 to B6 are coloured in red, blue, green, purple, orange, yellow and the HER2-positive group samples C1 to C6 are coloured in green, orange, blue, magenta, sea green, and yellow.