Figure 4.

Comparison of Mta and K-ZIP promoters. (A). Schematic of the −136/−62 Mta promoter. Sequences of the top and bottom strands of the indicated portion of the Mta promoter. Numbers indicate positions relative to Mta transcriptional start site. Bold letters indicate four units of the A/T₃ trinucleotide repeat. Underlines indicate Rta’s footprint from the bottom strand. Blue boxes indicate regions of highest conservation, nt 4–14, for each unit of the CANT repeat. The green box indicates the RBP-Jk binding site. The peach box indicates the AP-1 binding site. The yellow box indicates the K-RBP binding site. The red box indicates the IRF-7 binding site. The position of the short, Mta 5D element is indicated by the brackets. (B) Alignment of the top and bottom strands of the Mta and K-bZIP promoters. Numbering and box designations are as listed in the legend for Figure 3, above. The purple box indicates the Oct-1 binding site.