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. 2011 Sep 28;14(2):153–161. doi: 10.3109/14653249.2011.613930

Table I.

Comparison of fibrosis parameters between days 9 and 14 within each experimental group.

Bleo group Bleo + non-CM group Bleo + AMTC-CM group



Day 9 Day 14 Day 9 Day 14 Day 9 Day 14






M IQR M IQR P M IQR M IQR P M IQR M IQR P
Fibrosis distribution 1.5 1.0 3.0 1.8 < 0.05 1.0 0.5 2.5 2.0 < 0.01 1.0 0.3 1.0 0.9 NS
Fibroblast proliferation 0.7 0.4 1.6 1.0 < 0.01 0.2 0.3 1.5 1.2 < 0.01 0.7 0.5 0.8 0.4 NS
Collagen deposition 1.2 0.3 2.0 1.2 < 0.05 1.0 0.8 2.2 1.0 < 0.01 1.0 0.5 1.4 0.5 NS
Alveolar obliteration 2.7 0.8 3.2 0.5 NS 2.3 0.8 3.1 1.2 < 0.05 2.5 1.2 2.3 0.8 NS

Fibrosis progression was observed in the control groups (Bleo and Bleo + non-CM) from days 9 to 14, but was absent in the AMTC-CM treated group.

Median (M) with IQR of scores obtained from animals of the same group at each time-point. The statistical differences between time-points of each group are reported as P-values, which were calculated as described in the Methods. NS, not significant.