Table 1.

In vitro antibacterial activities of compounds 8a-q and 11

Compound	R	R 1	R 2	R 3	R 4	R 5	MIC (μg/mL)
							Ec	Pa	Sa	Kp
8a		H	H	H	H	H	> 50	> 50	50	12.5
8b		H	H	CF3	H	H	> 50	> 50	50	12.5
8c		H	H	Br	H	H	> 50	> 50	50	12.5
8d		H	H	Cl	H	H	> 50	> 50	> 50	12.5
8e		H	H	CH3	H	H	> 50	> 50	> 50	25
8f		H	H	F	H	H	> 50	> 50	> 50	50
8g		CF3	H	H	H	H	> 50	> 50	> 50	> 50
8h		F	F	F	F	F	> 50	> 50	> 50	> 50
8i		H	H	Br	H	H	> 50	> 50	> 50	> 50
8j		H	H	F	H	H	> 50	> 50	> 50	> 50
8k		H	H	Br	H	H	> 50	> 50	> 50	> 50
8l		H	H	CF3	H	H	> 50	> 50	> 50	> 50
8m		H	H	Br	H	H	> 50	> 50	> 50	> 50
8n		H	H	Cl	H	H	> 50	> 50	> 50	> 50
8o		H	Br	H	H	H	> 50	> 50	> 50	> 50
8p		H	Cl	H	H	H	> 50	> 50	> 50	> 50
8q		H	F	H	H	H	50	> 50	> 50	> 50
11	-	-	-	-	-	-	> 50	> 50	> 50	> 50
Gentamycin	-	-	-	-	-	-	0.78	0.78	0.39	0.78
Ampicillin	-	-	-	-	-	-	50	50	0.19	0.39

Ec, E. coli (ATCC 9637); Pa, P. aeruginosa (ATCC BAA-427); Sa, S. aureus (ATCC 25923); Kp, K. pneumonia (ATCC 27736)