Table 1.
Baseline characteristics of study population
| Variable | Cases (n= 485) | Controls (n = 1367) | P-value |
|---|---|---|---|
| Male | 409 (84.3%) | 1159 (84.8%) | 0.81 |
| Age (years) | 64.80 (7.83) | 64.65 (7.66) | 0.71 |
| Current smokers | 127 (26.2%) | 297 (21.7%) | 0.04 |
| Alcohol | |||
| Never | 124 (25.6%) | 298 (21.8%) | |
| ≤14/21 U/week | 270 (55.7%) | 803 (58.7%) | |
| >14/21 U/week | 91 (18.8%) | 266 (19.5%) | 0.23 |
| Completed education | 182 (37.5%) | 452 (33.1%) | |
| Age: ≤15 | 233 (48.0%) | 632 (46.2%) | |
| Age: ≤18 | 46 (9.5%) | 154 (11.3%) | |
| Age: 19+ | 24 (4.9%) | 129 (9.4%) | 0.007 |
| SBP (mmHg) | 164.61 (17.81) | 161.70 (17.48) | 0.002 |
| DBP (mmHg) | 92.95 (10.37) | 92.13 (9.83) | 0.12 |
| Heart rate (b.p.m.) | 69.65 (12.91) | 70.35 (11.85) | 0.28 |
| BMI (kg/m2) | 28.71 (4.05) | 29.00 (4.50) | 0.21 |
| Total cholesterol (mmol/L) | 5.99 (1.07) | 5.92 (1.07) | 0.21 |
| LDL-c (mmol/L) | 3.92 (0.97) | 3.79 (0.96) | 0.02 |
| HDL-cholesterol (mmol/L) | 1.26 (0.33) | 1.30 (0.34) | 0.02 |
| Loge triglyceride (mmol/L) | 0.52 (0.46) | 0.50 (0.49) | 0.44 |
| Loge C-reactive protein (mg/L) | 1.13 (0.98) | 0.95 (0.98) | 0.0006 |
| Loge glucose (mmol/L) | 1.82 (0.31) | 1.78 (0.28) | 0.03 |
| Creatinine (mmol/L) | 102.34 (19.31) | 99.23 (16.57) | 0.0008 |
| Diabetes | 150 (30.9%) | 356 (26.0%) | 0.038 |
| Family history CHD | 85 (17.5%) | 233 (17.0%) | 0.81 |
| Amlodipine | 227 (46.8%) | 694 (50.8%) | 0.13 |
| Atorvastatina | 101 (43.0%) | 407(52.4%) | 0.01 |
Values are mean (SD) or n (%). Missing: LDL-c, 121; triglycerides, 79; fasting glucose, 84; creatinine, 45; C-reactive protein, 4.
aTwo hundred and thirty-five cases and 777 controls participated in lipid-lowering arm.