Table 4.
Comparative clinical parameter with carrier and non carrier Xmn1in HbSβ –thalassemia patients.
| Frequency % | |||
|---|---|---|---|
|
| |||
| Clinical Parameters | Xmn-1 (+/+) N=24 |
Xmn-1 (+/−) N=30 |
Xmn-1 (−/−) N=21 |
| Anemia | 11 (45.83%) | 16 (53.33 %) | 14 (66.66 %) |
| Hepatomegaly | 3 (15.78%) | 8 (26.66 %) | 5 (23.8%) |
| Splenomegaly | 6 (25 %) | 9 (30%) | 7 (33.34%) |
| Painful crisis | 7 (29.16 %) | 9 (30 %) | 10 (47.61 %) |
| Gall stone | 6 (25 %) | 8 (26.66%) | 7 (33.33%) |
| Acute chest syndrome | 5 (20.84%) | 7 (23.34%) | 7 (33.34) |
| Jaundice | 4 (16.67%) | 6 (20%) | 5 (23.8%) |
| Hyper pigmentation | 2 (8.33%) | 3 (10%) | 2 (9.52 %) |
| Avascular necrosis | 1 (4.16%) | 3 (10 %) | 2(9.52 %) |
| Retinopathy | None | 2 (6.66 %) | 1 (4.76 %) |
| Septicemia | 2 (8.33 %) | 1 (3.33 %) | None |
| Deep vein thrombosis | 1 (4.16 %) | None | 1 (4.76%) |
| Leg ulcer | 2 (8.33 %) | 1 (3.33 %) | 2 (9.52 %) |
| Frequency of blood transfusion | 9 (37.5 %) | 13 (43.33%) | 10 (47.61 %) |