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. 2012 Feb 14;6(2):e1474. doi: 10.1371/journal.pntd.0001474

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Portela et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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S. mansoni females treated with PA1259 at 50 µg/mL (A, C, and E), compared to control worms (B and D). Hz stands for hemozoin. In B and D: black Hz in a well defined gut; in C: Few minutes after treatment, Hz turns to brown inside the gut; in E) one hour after treatment the brown pigment was transfered outside of the gut.