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. 2011 Oct 13;120(2):267–274. doi: 10.1289/ehp.1104055

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Differential role of mitochondrial H₂O₂ in 1,2‑NQ–induced gene expression in BEAS-2B cells pretreated with DMSO vehicle, the mitochondrial complex I inhibitor rotenone (Rot; 10 µM, 30 min), or H₂O₂ (30 µM, 10 sec) prior to the addition of 10 µM 1,2‑NQ for 4 hr. mRNA levels of IL-8 (A,D), COX‑2(B,E), and HO-1 (C,F) were measured using TaqMan-based RT-PCR, normalized to levels of β-actin mRNA, and expressed as fold increases over vehicle control (mean ± SE; n = 3). **p < 0.01.