Table 2. Correlations of Soluble RAGE With Other Variables.
| Variable |
Pre-phase |
Pre- and post-change |
| r (P value) | r (P value) | |
| Age, years | 0.068 (0.722) | 0.188 (0.318) |
| Gender, male | -0.063 (0.742) | 0.011 (0.955) |
| Body mass index, kg/m² | -0.512 (0.004)** | -0.191 (0.313) |
| Systolic blood pressure, mmHg | 0.048 (0.800) | 0.135 (0.476) |
| Diastolic blood pressure, mmHg | -0.071 (0.710) | 0.174 (0.358) |
| LDL-cholesterol, mmol/L | -0.080 (0.673) | -0.230 (0.221) |
| Triglycerides, mmol/L | -0.050 (0.792) | 0.123 (0.516) |
| HDL-cholesterol, mmol/L | -0.154 (0.418) | -0.189 (0.317) |
| Fasting plasma glucose, mmol/L | -0.021 (0.912) | -0.030 (0.874) |
| Insulin, µU/mL | -0.290 (0.120) | 0.041 (0.829) |
| HOMA-IR | -0.365 (0.047)* | -0.013 (0.944) |
| PON1, UL | -0.166 (0.381) | -0.511 (0.004)** |
RAGE: the receptor for advanced glycation end product; LDL: low-density lipoprotein; HDL: high-density lipoprotein; HOMA-IR: homeostasis model assessment of insulin resistance; PON1: paraoxonase1; Pre-phase: correlation between the pre-phase data in respective variables; Pre- and post-change: correlation between the level changes (the post-phase data minus the pre-phase data) in respective variables (age and gender used the pre-phase data were); r: simple linear regression coefficient between soluble RAGE and another variable; β: multiple linear regression coefficient in a stepwise multivariate analysis for soluble RAGE after controlling for all the listed variables (except for HOMA-IR).
Triglycerides, insulin and HOMA-IR were log-transformed for the analyses.
Significance level: *P < 0.05; **P < 0.01.