TABLE 1.
Baseline characteristics of the DPP participants enrolled in the genetic study
| Overall | Placebo | Metformin | Lifestyle | |
|---|---|---|---|---|
| n | 2,994 | 1,000 | 990 | 1,004 |
| Sex | ||||
| Male | 982 (32.8) | 311 (31.1) | 344 (34.7) | 327 (32.6) |
| Female | 2,012 (67.2) | 689 (68.9) | 646 (65.3) | 677 (67.4) |
| Race or ethnic group | ||||
| White | 1,674 (55.9) | 557 (55.7) | 570 (57.6) | 547 (54.5) |
| African American | 612 (20.4) | 210 (21.0) | 206 (20.8) | 196 (19.5) |
| Hispanic | 498 (16.6) | 164 (16.4) | 158 (16.0) | 176 (17.5) |
| Asian/Pacific Islander | 128 (4.3) | 39 (3.9) | 33 (3.3) | 56 (5.6) |
| American Indian | 82 (2.7) | 30 (3.0) | 23 (2.3) | 29 (2.9) |
| Family history of diabetes | 2,089 (69.8) | 703 (70.4) | 683 (69.0) | 703 (70.1) |
| History of gestational diabetes mellitus | 321 (16.0) | 105 (15.2) | 104 (16.1) | 112 (16.5) |
| Quantitative traits | ||||
| Age (years) | 50.8 ± 10.7 | 50.5 ± 10.5 | 51.0 ± 10.4 | 50.7 ± 11.4 |
| Weight (kg) | 94.6 ± 20.3 | 94.8 ± 20.2 | 94.6 ± 20.0 | 94.5 ± 20.8 |
| BMI (kg/m2) | 34.1 ± 6.7 | 34.3 ± 6.7 | 34.0 ± 6.7 | 34.0 ± 6.8 |
| Waist circumference (cm) | 105.2 ± 14.6 | 105.3 ± 14.5 | 105.0 ± 14.6 | 105.3 ± 14.9 |
| Waist-to-hip ratio | 0.92 ± 0.09 | 0.92 ± 0.08 | 0.93 ± 0.09 | 0.93 ± 0.09 |
| Plasma glucose (mg/dl) | ||||
| In the fasting state | 106.7 ± 8.2 | 107.0 ± 8.4 | 106.7 ± 8.4 | 106.5 ± 7.9 |
| 2 h after an oral glucose load | 164.7 ± 17.1 | 164.6 ± 17.2 | 165.1 ± 17.2 | 164.4 ± 16.9 |
| Glycated hemoglobin (%) | 5.91 ± 0.51 | 5.91 ± 0.50 | 5.91 ± 0.51 | 5.91 ± 0.51 |
| Leisure physical activitiy (MET h/week) | 16.1 ± 25.9 | 16.6 ± 29.1 | 16.4 ± 25.9 | 15.4 ± 22.4 |
Data are n (%) or means ± SD.