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CaD prevents the decrease in occludin and claudin-5 protein levels in the rat retinas induced by diabetes. ZO-1 levels were not significantly changed. Tight junction protein levels were assessed by Western blotting. A representative Western blot is shown above each graph. Data are presented as percentage of control and represent the mean ± SEM of 7–9 animals. *P < 0.05, **P < 0.01, significantly different from control; ANOVA (one-way) followed by Dunnett post hoc test.
