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. 2010 Aug 3;59(10):2579–2587. doi: 10.2337/db10-0476

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© 2010 by the American Diabetes Association.

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FIG. 3. — Reduced promoter activity of Mafa in NOD mice. A: Localization of sequence variants of Mafa in NOD mice. B: Comparison of Mafa sequences in BALB/c, C3H, CTS, NSY, and NOD mice. Numbers represent position of each variant relative to transcription start site. C: Constructs of luciferase reporter plasmids. D: Comparison of promoter activity of mMafa-p-luc between BALB/c and NOD mice. Data are expressed as means ± SE. *P < 0.001, Student t test. E: Comparison of promoter activity of mMafa-p-lucΔClaI-ΔSfiI between BALB/c and NOD mice. Data are expressed as means ± SE.