Figure 2. p66-KO mice showed less severe clinical EAE compared to WT mice.
Immunized p66-KO and WT mice were scored daily for clinical signs of weakness and paralysis over a 36-day observation period. Throughout the entire clinical course, mean p66-KO scores were less than the WT scores. At the end of the 36 days, the p66-KO mice had significantly lower scores compared to the WT mice, reflecting the overall trend of reduced clinical impairment.