Table 2.
bax/ß-actin | bcl-2/ß-actin | bax/ß-actin to bcl-2/ß-actin ratio | ||||
---|---|---|---|---|---|---|
Day | Control | z-VAD | Control | z-VAD | Control | z-VAD |
4 | 0.57 ± 0.03 | 0.56 ± 0.06 | 0.47 ± 0.06 | 0.50 ± 0.08 | 1.31 ± 0.18 | 1.18 ± 0.14 |
14 | 0.68 ± 0.05 | 0.74 ± 0.05 | 0.61 ± 0.09 | 0.63 ± 0.08 | 1.22 ± 0.16 | 1.25 ± 0.15 |
Animals underwent muscle injury and treatment with DMSO as vehicle solution (control) or pan-caspase inhibitor z-VAD.fmk (z-VAD). Analysis was performed at day 4 and 14 after injury. Data are given as mean ± SEM; n = 6 per time point and group; t-test; no statistical significances were found