Table 4.

Characteristics of Autism in Subgroups at Baseline in Subjects with Autism

A. Defined by Median Split of Serum Epithelial Growth Factor (EGF) Levels
Clinical tests for autism	EGF median split	Mean	SD	n	p value*
ADI-R	Below	25.4	3.5	37	0.08
	Above	26.8	3.6	38
ABC
Irritablility	Below	27.1	6.3	37	0.59
	Above	28.0	6.9	38
Social withdrawal	Below	17.4	7.5	37	0.36
	Above	19.1	8.6	38
Stereotypy	Below	10.9	4.9	37	0.48
	Above	10.1	4.9	37
Hyperactivity	Below	31.8	9.3	37	0.32
	Above	33.8	8.1	38
Inappropriate speech	Below	6.3	4.1	37	0.23
	Above	5.2	4.0	37
VABS
Communication domain	Below	46.1	15.4	37	0.45
	Above	43.2	17.1	38
Social domain	Below	50.6	14.2	37	0.52
	Above	48.5	13.7	38
Daily living	Below	40.0	20.5	37	0.91
	Above	39.4	18.8	38

B. Defined by Medium Split of Serum Interleukin-13 Levels
Clinical tests for autism	IL-13 median split	Mean	SD	n	p value*
ADI-R	Below	25.7	3.7	38	0.31
	Above	26.6	3.3	39
ABC
Irritablility	Below	26.6	7.0	38	0.3
	Above	28.2	6.1	39
Social withdrawal	Below	19.1	7.9	38	0.25
	Above	16.9	8.2	36
Stereotypy	Below	10.4	5.3	38	0.91
	Above	10.5	4.5	38
Hyperactivity	Below	32.7	8.4	38	0.9
	Above	32.9	9.1	39
Inappropriate speech	Below	5.1	4.0	38	0.17
	Above	6.4	4.0	38
VABS
Communication domain	Below	44.8	17.6	38	0.88
	Above	44.2	14.5	39
Social domain	Below	49.4	14.4	38	0.93
	Above	49.6	13.2	39
Daily living	Below	39.2	20.0	38	0.92
	Above	39.7	19.1	39

^*Student's t-test, alpha=0.05.

SD=standard deviation; ADI-R=Autism Diagnostic Interview-Revised; ABC=Aberrant Behavior Checklist; VABS=Vineland Adaptive Behavior Scales.